Research

It’s important to note that many of these articles use creatine monohydrate (CM) for testing and that any efficacy demonstrated by CM is only enhanced with C-HCl since C-HCl has far better uptake (i.e. more positive effects with lower doses).

stone, balance, rock

Creatine HCL Stability Narrative

White paper prepared by Donald W. Miller, ph.D.
Professor

Department of Pharamacology and Therapeutics
University of Manitoba
Based on Patented “Creatine Hydrochloride”

calm, water, clear

Comparison of Solubility

Comparison of Solubility of Various Forms of Creatine as a Means of Determining Bioavailability

White Paper prepared by Reed, N., Pridemore, H., Saleh, S., et al; in conjunction with Vanderbilt University Dept. of Analytical Chemistry

Creatine Powder

Creatine HCL Supplementation

White paper prepared by Mark Faulkner, Inventor & Patent Holder
An improved form of orally ingested creatine

Unflavored Con-cret Creatine

CON-CRET® - Creatine Micro-Dosing® Dietary Supplement

White paper prepared by Donald W. Miller, ph.D.
Professor

Department of Pharamacology and Therapeutics
University of Manitoba
Based on Patented “Creatine Hydrochloride”

weak remedy, medicine, no person

Oral Bioavailability of Creatine Supplements: Is There Room for Improvement?

White paper prepared by Donald W. Miller, ph.D.
Professor

Department of Pharamacology and Therapeutics
University of Manitoba

cyber security, protection, technology

Creatine HCl as "GRAS"

(Generally Recognized as Safe)
By Prevailing Opinion of the Scientific Community

tags, active, athlete

Creatine HCL VS Creatine Monohydrate

White paper prepared by Jim Stoppani, pH.D.

water, glass, drip

Creatine Solubility Study

White paper prepared by Donald W. Miller, ph.D.
Professor

Department of Pharamacology and Therapeutics
University of Manitoba

salt, sea salt, salt crystals

Physicochemical Characterization of Creatine N-Methylguanidinium Salts

White paper prepared by
Brandon T. Gufford
Kamaraj Sriraghavan
Nicholas J. Miller
Donald W. Miller
Xiaochen Gu
Jonathan L. Vennerstrom
Dennis H. Robinsona

Department of Pharmacology and Therapeutics, University of Manitoba
Pharmaceutical Analysis Laboratory, University of Manitoba
Department of Pharmaceutical Sciences, University of Nebraska Medical Center

salt, grains of salt, cooking ingredients

Absolute Oral Bioavailability of Creatine Monohydrate in Rats: Debunking a Myth

White paper prepared by
Eman A. Alraddadi 
Ryan Lillico
Jonathan L. Vennerstrom 
Ted M. Lakowski
Donald W. Miller

Department of Pharmacology and Therapeutics, University of Manitoba
Pharmaceutical Analysis Laboratory, University of Manitoba
Department of Pharmaceutical Sciences, University of Nebraska Medical Center

gears, silhouettes, man

First use of creatine hydrochloride in premanifest Huntington disease

Case Study by Chris Tuckfield
MB BS(Hons), MPhil
Paddington Medical Centre,
Sydney, NSW
Medical Journal of Australia 

crystal grid, molecular grid, black background

Special Issue "Creatine Supplementation for Health and Clinical Diseases"

Nutrients (ISSN 2072-6643; CODEN: NUTRHU) is a peer-reviewed, open access journal of human nutrition published monthly online by MDPI. Nutrients released a special issue about creatine.