Research
It’s important to note that many of these articles use creatine monohydrate (CM) for testing and that any efficacy demonstrated by CM is only enhanced with C-HCl since C-HCl has far better uptake (i.e. more positive effects with lower doses).
Creatine HCL Stability Narrative
White paper prepared by Donald W. Miller, ph.D.
Professor
Department of Pharamacology and Therapeutics
University of Manitoba
Based on Patented “Creatine Hydrochloride”
Comparison of Solubility
Comparison of Solubility of Various Forms of Creatine as a Means of Determining Bioavailability
White Paper prepared by Reed, N., Pridemore, H., Saleh, S., et al; in conjunction with Vanderbilt University Dept. of Analytical Chemistry
Creatine HCL Supplementation
White paper prepared by Mark Faulkner, Inventor & Patent Holder
An improved form of orally ingested creatine
CON-CRET® - Creatine Micro-Dosing® Dietary Supplement
White paper prepared by Donald W. Miller, ph.D.
Professor
Department of Pharamacology and Therapeutics
University of Manitoba
Based on Patented “Creatine Hydrochloride”
Oral Bioavailability of Creatine Supplements: Is There Room for Improvement?
White paper prepared by Donald W. Miller, ph.D.
Professor
Department of Pharamacology and Therapeutics
University of Manitoba
Creatine HCl as "GRAS"
(Generally Recognized as Safe)
By Prevailing Opinion of the Scientific Community
Creatine Solubility Study
White paper prepared by Donald W. Miller, ph.D.
Professor
Department of Pharamacology and Therapeutics
University of Manitoba
Physicochemical Characterization of Creatine N-Methylguanidinium Salts
White paper prepared by
Brandon T. Gufford
Kamaraj Sriraghavan
Nicholas J. Miller
Donald W. Miller
Xiaochen Gu
Jonathan L. Vennerstrom
Dennis H. Robinsona
Department of Pharmacology and Therapeutics, University of Manitoba
Pharmaceutical Analysis Laboratory, University of Manitoba
Department of Pharmaceutical Sciences, University of Nebraska Medical Center
Absolute Oral Bioavailability of Creatine Monohydrate in Rats: Debunking a Myth
White paper prepared by
Eman A. Alraddadi
Ryan Lillico
Jonathan L. Vennerstrom
Ted M. Lakowski
Donald W. Miller
Department of Pharmacology and Therapeutics, University of Manitoba
Pharmaceutical Analysis Laboratory, University of Manitoba
Department of Pharmaceutical Sciences, University of Nebraska Medical Center
First use of creatine hydrochloride in premanifest Huntington disease
Case Study by Chris Tuckfield
MB BS(Hons), MPhil
Paddington Medical Centre,
Sydney, NSW
Medical Journal of Australia
Special Issue "Creatine Supplementation for Health and Clinical Diseases"
Nutrients (ISSN 2072-6643; CODEN: NUTRHU) is a peer-reviewed, open access journal of human nutrition published monthly online by MDPI. Nutrients released a special issue about creatine.