Creatine Overview

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Creatine Monohydrate vs
Creatine Hydrochloride

Why Creatine HCl?
Creatine HCl is proven to be the most bioavailable (soluble) form of creatine. It is 59x more soluble than other creatines which means the body absorbs it faster & uses it more efficiently.

Creatine Hydrochloride (HCl)

Creatine HCl delivers safe, effective, and dramatic results in increased strength, endurance, and muscle recovery…with none of the negative side effects typical of other creatines (bloating, cramping, GI issues, water retention, etc). It’s the only creatine that is dosed per body weight — ¼ teaspoon per 100 lbs of body weight.

It has proven to be the most soluble and potent creatine on the market and was proven in multiple academic studies to be at least 59X more soluble* than creatine monohydrate.  This is significant because creatines vary in performance largely based on solubility. The reason solubility is crucial is that when you increase creatine solubility (the ability to dissolve), you enhance creatine delivery (absorption into body and ultimately into the muscles).

The results of these studies catalyzed another study on bioavailability and plasma uptake conducted by researchers from two major universities and performed by testing blood plasma in human subjects after oral dosing.  These findings were presented at the ISSN Conference in June 2009.  The results of this second study showed convincing evidence of a significant improvement in plasma uptake with creatine hydrochloride.  In the study, Creatine HCl demonstrated up to 70% increase** in plasma uptake compared to creatine monohydrate (CM).  These results reinforced the notion that Creatine HCl is the most readily absorbed creatine form available.  This fact is the reason that Creatine HCl does not require loading of large initial doses or cycling on and off the supplement.  Creatine HCl is available in powder and capsule forms, and each serving of Creatine HCl is equivalent to the potency of over 3 – 5 grams of creatine monohydrate.  It is safe to take every day.

Other Common Creatines

Creatine Monohydate

Creatine monohydrate is the most popular form of creatine and has proven to show great benefits for athletes looking to increase strength and muscle performance.  The shortfalls of creatine monohydrate have been attributed to its limited absorption due to low bioavailability.  Therefore, athletes are required to take large amounts of up to 10 grams for the first two weeks, and then cycle off for the digestive and muscular system to take a break.

Studies have shown that consumption of creatine monohydrate does not cause any serious adverse side effects. However, some people experience muscle cramping, bloat, stomach and digestive discomfort, including possibly diarrhea, for a few weeks when using creatine monohydrate. The digestive and stomach problems may be eradicated by lowering the amount of intake of creatine monohydrate but that reduces the effective amount of creatine being delivered to the cells of the body.  Since creatine supplementation causes the muscles to retain water, some people may experience weight gain and may also become dehydrated from cellular fluid redistribution.

pH Buffered Creatine

pH Buffered Creatine is a buffered creatine that claims it does not turn into creatinine prior to reaching skeletal muscle tissue.  It is touted to have a higher pH level than regular creatine monohydrate.  The philosophy is that the conversion of creatine into creatinine is a function of the pH and can be halted by pH level manipulation during the manufacturing process.  However, this is simply creatine monohydrate mixed (not conjugated) with a buffering agent like magnesium phosphate, or such.  While that will buffer the liquid into which creatine monohydrate is introduced, it does not change the solubility of the creatine monohydrate molecule and once ingested, the stomach acid immediately overwhelms the buffering agent and you’re left with creatine monohydrate in the gut with limited absorption.